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Syed, A., Zhai, J., Guo, B., Zhao, Y., Wang, J., Chen, L. 2024. Cryo-EM structure and molecular dynamic simulations explain the enhanced stability and ATP activity of the pathological chaperonin mutant. Structure.
Chen, L., Syed, A., Balaji, A. 2022. Hereditary spastic paraplegia SPG13 mutation increases structural stability and ATPase activity of human mitochondrial chaperonin. Scientific Reports.
Wang, J.CY., Chen, L. 2021. Structural basis for the structural dynamics of human mitochondrial chaperonin mHsp60. Scientific Reports.
Illingworth M, Ellis H, and Chen L. 2017. Creating the Functional Single-Ring GroEL-GroES Chaperonin Systems via Modulating GroEL-GroES Interaction. Scientific Reports.
Illingworth, M., Hooppaw, A. J., Ruan, L., Fisher, D. J., and Chen, L. 2017. Biochemical and Genetic Analysis of the Chlamydia GroEL Chaperonins. Journal of Bacteriology.
Illingworth, M., Salisbury, J., Li, W., Lin, D., and Chen, L. 2015. Effective ATPase activity and moderate chaperonin-cochaperonin interaction for the functional single-ring chaperonin system. Biochemical and Biophysical Research Communications, in press.
Pan, Y., Wang, Y., Fuquq, C., and Chen, L. 2013. In vivo analysis of DNA binding and ligand interactions of BlcR, an IlcR-type repressor from Agrobacterium tumefaciens. Microbiology SGM 159 (4): 814-822.
Zheng, Z., Fuqua, C., and Chen, L. 2012. The binding site of DNA on quorum-sensing transcript factor TraR does not overlap with that of the Anti-Activator. Biochemical and Biophysical Research Communications 418 (2): 396-401.
Zheng, Z., Ma, D., Yahr, T.L., and Chen, L. 2012. The transiently ordered regions in intrinsically disordered ExsE are correlated with structural elements involved in chaperone binding. Biochemical and Biophysical Research Communications 417 (1): 129-134.
Pan, Y., Fiscus, V., Meng, W., Zheng, Z., Zhang, L-H., Fuqua, C., and Chen, L. 2011. The Agrobacterium tumefaciens transcription factor BlcR is regulated via oligomerization. Journal of Biological Chemistry 286 (23): 20431–20440.
Churchill, M.E.A. and Chen, L. 2011. Structural basis of acyl-homoserine lactone-dependent signaling. Chemical Reviews 111 (1): 68– 85.
Li, Y., Zheng, Z., Ramsey, A., and Chen, L. 2010. Analysis of peptides and proteins in their binding to GroEL. Journal of Peptide Science 16 (12): 693- 700.
Chen, L. 2010. Signal synthesis for a rapid response. Structure 18 (9): 1072- 1073.
Li, Y. Gao, X., and Chen, L. 2009. GroEL recognizes an amphipathic helix and binds to the hydrophobic side. Journal of Biological Chemistry 284 (7): 4324–4331.
Zheng, Z., Chen, G., Joshi, S., Brutinel, E.D., Yahr, T.L., and Chen, L. 2007. Biochemical characterization of a regulatory cascade controlling transcription of the Pseudomonas aeruginosa type III secretion system. Journal of Biological Chemistry 282 (9): 6136– 6142.
Chen, G., Jeffrey, P.D., Fuqua, C., Shi, Y., and Chen, L. 2007. Structural basis for antiactivation in bacterial quorum sensing. PNAS 104 (42): 16474– 16479.
Banga, S., Gao, P., Shen, X., Fiscus, V., Zong, W-X., Chen, L., and Luo, Z-Q. 2007. Legionella pneumophila inhibits macrophage apoptosis by targeting pro-death members of the Bcl2 protein family. PNAS 104 (12): 5121– 5126.
Wang, C., Zhang, H-B., Chen, G., Chen, L., and Zhang, L-H. 2006. Dual control of quorum sensing by two TraM-type antiactivators in Agrobacterium tumefaciens octopine strain A6. Journal of Bacteriology 188 (7): 2435– 2445.
Lykken, G.L., Chen, G., Brutinel, E.D., Chen, L., and Yahr, T.L. 2006. Characterization of ExsC and ExsD self-association and heterocomplex formation. Journal of Bacteriology 188 (19): 6832– 6840.
Chen, G., Wang, C., Fuqua, C., Zhang, L-H., and Chen, L. 2006. Crystal structure and mechanism of TraM2, a second quorum-sensing antiactivator of Agrobacterium tumefaciens strain A6. Journal of Bacteriology 188 (23): 8244– 8251.
Chen, G., Malenkos, J.W., Cha, M-R., Fuqua, C., and Chen, L. 2004. Quorum-sensing antiactivator TraM forms a dimer that dissociates to inhibit TraR. Molecular Microbiology 52 (6): 1641– 1651.
