Syed, A., Zhai, J., Guo, B., Zhao, Y., Wang, J., Chen, L. 2024. Cryo-EM structure and molecular dynamic simulations explain the enhanced stability and ATP activity of the pathological chaperonin mutant. Structure.
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Chen, L., Syed, A., Balaji, A. 2022. Hereditary spastic paraplegia SPG13 mutation increases structural stability and ATPase activity of human mitochondrial chaperonin. Scientific Reports.
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Wang, J.CY., Chen, L. 2021. Structural basis for the structural dynamics of human mitochondrial chaperonin mHsp60. Scientific Reports.
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Illingworth M, Ellis H, and Chen L. 2017. Creating the Functional Single-Ring GroEL-GroES Chaperonin Systems via Modulating GroEL-GroES Interaction. Scientific Reports.
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Illingworth, M., Hooppaw, A. J., Ruan, L., Fisher, D. J., and Chen, L. 2017. Biochemical and Genetic Analysis of the Chlamydia GroEL Chaperonins. Journal of Bacteriology.
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Illingworth, M., Salisbury, J., Li, W., Lin, D., and Chen, L. 2015. Effective ATPase activity and moderate chaperonin-cochaperonin interaction for the functional single-ring chaperonin system. Biochemical and Biophysical Research Communications, in press.
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Pan, Y., Wang, Y., Fuquq, C., and Chen, L. 2013. In vivo analysis of DNA binding and ligand interactions of BlcR, an IlcR-type repressor from Agrobacterium tumefaciens. Microbiology SGM 159 (4): 814-822.
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Zheng, Z., Fuqua, C., and Chen, L. 2012. The binding site of DNA on quorum-sensing transcript factor TraR does not overlap with that of the Anti-Activator. Biochemical and Biophysical Research Communications 418 (2): 396-401.
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Zheng, Z., Ma, D., Yahr, T.L., and Chen, L. 2012. The transiently ordered regions in intrinsically disordered ExsE are correlated with structural elements involved in chaperone binding. Biochemical and Biophysical Research Communications 417 (1): 129-134.
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Pan, Y., Fiscus, V., Meng, W., Zheng, Z., Zhang, L-H., Fuqua, C., and Chen, L. 2011. The Agrobacterium tumefaciens transcription factor BlcR is regulated via oligomerization. Journal of Biological Chemistry 286 (23): 20431–20440.
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Churchill, M.E.A. and Chen, L. 2011. Structural basis of acyl-homoserine lactone-dependent signaling. Chemical Reviews 111 (1): 68– 85.
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Li, Y., Zheng, Z., Ramsey, A., and Chen, L. 2010. Analysis of peptides and proteins in their binding to GroEL. Journal of Peptide Science 16 (12): 693- 700.
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Chen, L. 2010. Signal synthesis for a rapid response. Structure 18 (9): 1072- 1073.
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Li, Y. Gao, X., and Chen, L. 2009. GroEL recognizes an amphipathic helix and binds to the hydrophobic side. Journal of Biological Chemistry 284 (7): 4324–4331.
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Zheng, Z., Chen, G., Joshi, S., Brutinel, E.D., Yahr, T.L., and Chen, L. 2007. Biochemical characterization of a regulatory cascade controlling transcription of the Pseudomonas aeruginosa type III secretion system. Journal of Biological Chemistry 282 (9): 6136– 6142.
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Chen, G., Jeffrey, P.D., Fuqua, C., Shi, Y., and Chen, L. 2007. Structural basis for antiactivation in bacterial quorum sensing. PNAS 104 (42): 16474– 16479.
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Banga, S., Gao, P., Shen, X., Fiscus, V., Zong, W-X., Chen, L., and Luo, Z-Q. 2007. Legionella pneumophila inhibits macrophage apoptosis by targeting pro-death members of the Bcl2 protein family. PNAS 104 (12): 5121– 5126.
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Wang, C., Zhang, H-B., Chen, G., Chen, L., and Zhang, L-H. 2006. Dual control of quorum sensing by two TraM-type antiactivators in Agrobacterium tumefaciens octopine strain A6. Journal of Bacteriology 188 (7): 2435– 2445.
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Lykken, G.L., Chen, G., Brutinel, E.D., Chen, L., and Yahr, T.L. 2006. Characterization of ExsC and ExsD self-association and heterocomplex formation. Journal of Bacteriology 188 (19): 6832– 6840.
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Chen, G., Wang, C., Fuqua, C., Zhang, L-H., and Chen, L. 2006. Crystal structure and mechanism of TraM2, a second quorum-sensing antiactivator of Agrobacterium tumefaciens strain A6. Journal of Bacteriology 188 (23): 8244– 8251.
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Chen, G., Malenkos, J.W., Cha, M-R., Fuqua, C., and Chen, L. 2004. Quorum-sensing antiactivator TraM forms a dimer that dissociates to inhibit TraR. Molecular Microbiology 52 (6): 1641– 1651.
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